Stanton Honig, MD Professor of Urology Director of Men's Health . My uro. Both in tests and real-world settings, the majority of patients who took Trimix experienced noticeable effects. It is only suitable for patients who have had no success with oral ED medications. mcg or micrograms a measure of mass, equivalent to 1/100, units in the case of Trimix and other injectable medications, this is a term synonymous with micrograms. An Unexpected Diagnosis Of Prostate Cancer. I have been suffering from progressive ED for the past 10 years. I have been researching and speaking out about penile rehab for almost a year, andthis is something I will definitely be focusing on here. ED Forum (Viagra, Cialis, Trimix, Implants). I am in UK ,where our health system is different to yours. The price of about quadmjx is close to $400 and dont want to pay that. At $120 for each prescription this is $7.50 per shot. Any thoughts? There is no set dosage; instead, it is usually adjusted gradually based on feedback from the patient and the physician. When administering an injection, especially in such a delicate location, always employ good cleanliness and safety precautions. My husband had had an RP about 10 months before (Oct. 15, 05), and since then we had not had normal sex. -------Hot & Popular Forum Discussions-------. I have erections that last a couple of hours, depending on stimulation. After a nerve sparing Prostatectomy, will injections help recovery of my natural erections? Eventuallywe found a top-notch ED doctor who gavedear husband an injectible potioncalled Trimix. Monochromatic, pink and purple tones. I am 74, and my wife is 69. Answer. And with Trimix *you* are in control. Thats why you should never rely on Internet searches or articles like this alone to determine how many units of Trimix are suitable. I suspect that when you injected and got no results you missed and when you injected and it wouldn't go down you were possibly ingesting a Nitric Oxide booster. Copyright 2016 FrankTalk.org All rights reserved. I had just received a phone call from my General Practioner to say they will NOT prescribe the cialis that my consultant ( we refer to specialist sugeon as our consultant ) had prescribed might help my/our problem. However, the vast majority of persons taking Trimix do not experience any such issues if the proper dosage and administration instructions, precautions, and other guidelines are followed. Trimix is slowly becoming unobtainable because of cost. This is in response to Steve, May 21, 2011, just to clarify. Trimix Injections are used as a second-line treatment when oral ED medications dont work. So an experimentation time is required for each person to get the correct formulation. Get the TRUTH about Trimix. Since our clinic is not driven by sales/profit we are more focused on safety and success, in that order. After an orgasm or ejaculation, the subsequent erection often lasts for one to two hours and may or may not disappear. Fast forward to the two-minute mark for the information. Do you know you mix ratio? Id given up on having a sex life, which is sad at 61 and sadder if youre wife is 39 and has a libido that doesnt have an off switch. see, see, told ya! Woke up with priaprisim and wound up in ER. You can go on forever as long as time is no object. Thank you for taking the lead on this. In this video we run through how to administer an intracavernosal injection (aka peinle injection) using a compounded preparation - whist there is a lot to t. (Adrenaline counteracts the effect of the trimix.) Pull back on the syringe plunger in a slow and steady motion until the prescribed dosage is achieved. But Trimix is cheaper than Caverject (alprostadil). In most cases, Trimix injection results in a hard and lasting erection. You should be sure to ask them any questions or seek any clarifications to ensure you are only administering the correct dosage, as higher dosages carry an increased risk of side effects including erections that require medical attention. They should not be shared with a friend. It will bend, as if its hitting a hard spot. That is the prostaglandin and in my blend, for instance, it is 10mcg. first off i cant believe i was afraid of this i felt nothing 28 gauge needle. It is a very potent mixture of three effective ED drugs, including phentolamine, papaverine, and alprostadil, which are only available by prescription. I want to remain sexually active and have tried ED pumps, gels, and even. The name TriMix alludes to the fact that this medication is a mix of three medications frequently used to help improve erectile function. Alternate right and left side of penis with each injection. Sometimes it takes a couple of attempts to get over the freaked-outedness enough for it to work. Purchased a needle-free Injex unit for $300. What Are the Success Rates of TriMix Injections for ED Treatment? What is sildenafil tablets 100mg used for? 62% of reviewers reported a positive experience, while 24% reported a negative experience. Time will tell. (That's why we hear so many stories about. Still the erection lasted almost 6 hours before relenting. Well, I took 30; close to 25 right? And I will have to remember to switch sides the urologist never mentioned that one. Because its generally more effective and powerful (and therefore, somewhat riskier), it is reserved as a secondary treatment for ED. In this video, our expert at The Novus Center, Stephanie Wolff, explains the pros and cons of. Been using TriMix5 for 10 months after trial and error ended up using 25 units for 30 minutes of pleasure . Trimix is a prescription drug, therefore it carries certain risks. Employee communication . How does Trimix compare to EDEX injections? No, not for me. After the dose is set, I will be getting 30 doses per month for 6 months. You dont go through the apprehension anxiety. The most common side effects are injection site pain, small amounts of bleeding immediately following administration, and some initial discomfort. Sourcing your Trimix through a licensed and reputable pharmacy, with a prescription, is the only way to go. They come in very small vials of dry Trimix for mixing when needed so you dont have to refrigerate a large batch. Or you can end up with a Leaning Tower of Penis., I just wrote to someone that Trimix could give an erection to acorpse who was doing his taxes:-)). For those of us that have been there can really appreciate the report. Sudafed is a known antidote for Trimix, but the pill version is slow acting unless you are taking it for the first time. Sadly I can only use my stick for a divining rod. Thank you. This signal can come in many forms, but it is often a hormone of some kind. I pay $80 for 11.5ml (Atro 52mcg/ml, Phen 0.9mg/ml, Pap 26mg/ml). its due to arrive this week and i cant wait to get with my wife for the first time in 4yrs. Once a patient decides they want to proceed with treatment they will purchase their medication and return for the 2nd step, a trial dose in the clinic. Sep 24, 2014. When I first started I followed the directions to inject at 9 and 3 oclock and had many misfires. The maximum dose is 0.50 cc. Dr prescribed Trimix in April. All I can say this works for me but may not work for everyone. INJECTION There MUST be 24 hours in between EACH injection. I dont just stab it in because a fine needle like this often bends and you wind up injecting just below the skin. Buy Trimix injection online for direct application on the penis makes it frequently more efficient at causing an erection suitable for sex than oral ED therapies. Sure, but if you can only have 3 injections a week, and not more than 2 in a row, then what? A more appropriate starting dose is 2.5 micrograms. Go talk with the doc again. the trimix $145 for 5 doses and $195 for the auto injector. If you are considering buying Trimix, and deciding if it might be right for you, then talk to your doctor. Be patient, you will get there!! Erections came in XL and above only. I have been using Tri Mix for several months. Overview of TriMix Injection Dosage Strengths of TriMix Injection. It WORKS waited a year before he gave trimix.works great but the only problem is it mostly last to long. We started with a conservative 0.3 and started to get some real action from 1.0ml up. Here's what you can expect to discuss with your doctor when inquiring about ED problems and Trimix: Cigar56 I noticed you are using the AutoJect EI. I had complete prostrate surgery in April at Mayo clinic. Any one have any experiences or comments to share about Trimix? Im only 61. Since The single dose of caverject causes pain, or aching in some, I elected to go straight to Trimix. Golfer, that doesnt sound quite right. Do not click on these links if you are offended by images typically seen on porn sites. Best Wishes, SueJean. This is a reply that may apply to many regarding Trimix and Penile injections in general. Wants me to try 10 cc again or go to 11 if 10 doesnt work. And yes, you can have soreness, but its not normal. How many units of Trimix should I take is the most frequently asked question regarding Trimix dosage. Like all guys, DH was not exactly keen on shooting up *there*. I had a prostatectomy via robotic surgery. I had a radical prostatectomy in March this year , was 66 in June and in the same month my wife and me passed our 41 anniversary .Phew ! Trimix, once injected, starts to work right away. For many guys, this is a more interesting and approachable option than having awkward in-person conversations with their doctors. Sex addiction, or compulsive sexual behavior disorder, has been difficult to define. A unit is specific for each drug, not a standard volume. it gives the provider a baseline representation of how each patient will respond to the medication alone (without sexual stimulation of any kind). Common dose amountsrange from 0.08 ml to 0.9 ml per administration, not more than once every 24 hours, usually twice weekly. We understand that local physicians are a very important part of health care. I am a diabetic, and I have ED. Dont give up.). It costs me $140. I tapered my trimix dose to get things in order. Next time used 10 cc again nothing happened. I must tell you, dear readers, that if you take a breather, a seventh-inning stretch so to speak, you *can* even have a double-header. More Than You Thought, But What About The Rest? My frist injection given to me to take home was 30 units.It lasted 6+ hrs. but, if this possibly could work, I was willing to try it. There are people in the group who are very knowledgeabe about this subject, although, like me, they are not docs. Only issue was getting my erection to go away and I started to panic after 3 and a half hours. I too enjoyed the minute by minute story, but didn't we have a similar discussion at GFMPH? How bad of an idea would it be to give my wife some T-cyp? We were advised to learn to use our bodies in different ways. It is truly wonderful as mentioned in earlier post. New to trimix. While other posters are talking about the doses, I want to give some information about the number of injections you should take. I use an Owen Mumford Autoject El. I suggest that you join the prostatepointers.org group called PC and intimacy. There are different strengths for Trimix. It black and blue last 2 times sinc using the super strong trimix. Prostaglandin E1 10 ug/ml. A doctor advising you to take, for example, 20 units of Trimix is saying you should be filling up a syringe with 20 mcg, or 1/5 mL of medication. Around 20 to 30 minutes before sexual activity, an injection is often administered in the middle third of the penis shaft, alternating sides and avoiding any veins. bypassed the Mega trimix (double strength) to the Super Mega (double again) Wow. Other methods have *not been proven* to do this. My uro started me on 40 units. Easier said than done. I cant stress this enough. (I use a few office rubber bands doubled over.) "935-1035 gf begging for mercy i cant take any more she says im done i cant walk." Thanks for the contribution of your couples journeyshared. d. Turn the vial with needle and syringe inserted upside down. But in the real world, it can take some time, and many have reported erections that neared priapism. Tried trimix at different strengths before finding that I am one of the 7% of users for whom the effects are negated by Cymbalta (may also be surpressed by naproxen or ibuprofen or other NSAIDS. A second injection may cause more . Users browsing this forum: Bing [Bot] and 2 guests. Would you like to be our test bunny? So I rhapsodized a bit about it in alt.impotence and alt.support.cancer.prostate. I would recommend Trimix to anyone that has ED. Thank you for sharing your experience with trimix. This is the standard 30-10-1 mix from Empower. they immediately went into the sales pitch for trimix and a auto injector. I used a 5/16 needle. A1. My first injection made me swell up. Nothing like a good successful round of sex to bring people to a whole new way of looking at things (I could never stick a needle there! Listen up! MEDICATION As the name suggests, Trimix includes 3 active ingredients, and as the vial sits in the refrigerator awaiting your next use gravity is constantly at work pulling those ingredients towards the bottom of the vial. This way a prescription will be written, forwarded to the compounding pharmacy that is linked to being filled, and then delivered to your house for effective administration. These medications include: Papaverine. Knock out the testosterone (HDT), and though there is something going on physically, there is almost nothing going on mentally (where it counts, IMHO). But after Dr. Melman gave him the first shot, his fears vanished. A penile implant is an effective treatment option for men for whom Trimix injections do not work well. Sign up for the free quarterly Advanced Prostate Cancer Newsletter. It typically contains a combination of three active ingredients that can help improve blood flow for an erection. Next time I may get more adventurous! My wife and I were resigned that we would make do and find other ways to please each other. Trimix works by the same broad processes as oral ED drugs like Viagra and Cialis, they primarily relax the blood vessels and enhance blood flow, despite the different administration methods. Host virtual events and webinars to increase engagement and generate leads. In my opinion, penile injections is the BEST treatment option available for ED. I was told to make changes in increments of 5 units at a time so yes, you should probably try 25 units next and see. I like the #31 diameter needle and rather than the 1/2 needle normally recommended, I use a 5/16 or 3/8. I am 52 and this stuff will works once you get the correct amount I am using 20 units and it will last till my wife saysI give and can't take it anymore. I am in UK ,where our health system is different to yours. TriMix is a compounded medication that is specially mixed by a qualified pharmacist based on your prescription. Trimix contains only three of the ingredients; alprostadil, papaverine and phentolamine. My doctor prescribed trimix and I have used it a few times, but it hasn't been a great experience. Trimix is considered very effective for treating ED. Thanks for all the info and glad it worked so well for you. I ended up driving to the ER to get a injection. Trimix Gel contains the same active ingredients that are found in our Trimix penile injections. I have had the medication frozen now for 16 months with very little decrease in effectiveness. This is my 4th month.Any suggestions. As I'm trying to find the right dosing, i have not attempted sex, once i find i will be ready the next day, or same day, then i need to wait, that would be my only thought for viagra, agree, hate those side affects. They premix the formula and provide individual syringes for each injection/application. It works. The syringe is the plastic part of the device that holds the liquid. Thanks. For this purpose, its useful to define a few terms and units, so that there is no confusion as to proper dosing amounts. Medals ? They used a quadmix which gave me a good response, and used the sonar again. as if the mix is either far too strong or gone to the wrong area. I prefer the semi auto injector to the fully auto because I inject low on one side and higher on the other side of my penis. When I missed it was when I injected into the wall and missed the Corpus cavernosum and that hurt. Anyway, them came August 13, my birthday,andDH got me a beautiful bouquet of flowers. I only need about 0.10cc vs 0.25cc early on of Trimix 1, (0.5mg Phentolamine, 10mg Papaverine and 5mcg PGE1) This formula has one of the lowest amount of PGE which causes pain in some users. Wow, your info is changing how I look at things. They tried to sign me up for their program, but I passed. I then went to .5 units, got some enlargement but not enough for erections. No, the first injection may have punctured the urethra or other tissue. Such fun! As Gene Devine said your response to the small dosage increases does not make sense. Wait! How watching pornography can cause erectile dysfunction. You have to be sure to do it on both sides of the penis. The key here is that the response can be unpredictable, erratic, and risky if the vial is not THOROUGHLY mixed prior to EVERY use to ensure uniformity of solution. I'll get him to go back to his doctor. Your response at those tiny dosage changes doesn't make sense. I was referred to your blog from the Circle and Im so glad to have found you. As mentioned above, libido is still a factor in it, which has meant getting the right dose has been a little tricky. So, about 4 months post op, my urologist shared with me about Trimix. Alprostadil is a common TriMix ingredient. Very sore took 1.5 hrs to go down. Leah: I appreciate your candor and Old Man Rivers willingness to share your findings. Since Trimix is a powerful medication, and the risk of side effects tends to increase as dosage increases, most prescribers will start patients out on a relatively small dose. TriMiX Injection: Papaverine HCl 150 mg, Phentolamine Mesylate 5 mg, Prostaglandin E1 50 mcg. However, the most common question people usually have about Trimix dosage is, How many units of Trimix should I take? In this guide, we will help to answer that question and explore why there is no one-size-fits-all answer. Most normal doses of Trimix are like 10 units to 50 units. In an ideal world, the Trimix injections wear down without any external help. Thanks! Fill out the form below, and one of our treatment specialists will contact you. Trimix injections can be used up to three times a week, with 24 hours between doses. For a better experience, please enable JavaScript in your browser before proceeding. Leah, Hi all, new guy here to Injection therapy. It was great! By the way Im a non smoker, minimal alcohol, body fat in the single digits, resting heart rate 48 bpm work out six times per week. Spelling is wrong yes I know! Thank you so much, you cant imagine how much youve helped people. Our patients typically are not using doses as high as the ones being quoted on this site. But when after almost 4 hours, it wouldn't die down no matter what, not even with two sudafed 30mg pills, I had to go to the clinic and they drew some blood from my penis and injected an antidote of the same sudafed. Havent tried the sample of EDEX yet but hope it works better . I am going to try 4.5 units tonight. Papaverine HCl 30 mg/ml. I have a strip of Allegra-D just in case. At the other end of the spectrum, is the older gentleman (greater than 75 years old) with . thanks. I was in the uros office, where I was testing a Tri-Mix injection. It may not display this or other websites correctly. The initial dose should be 0.05 cc to 0.2 cc, depending on the level of ED. dr recommended .3 of a dose to start after reading all the info here i decided that that dose was to much. But it not like the good old days. The onset of an erection occurred within minutes and lasted over an hour. Hi, My husband at first used trimix 15 units with not good results..now uses super quad only 3 units and is maintaining for about, Since he is still using trimix I assume that there is nothing hopeful going on without it -- no nocturnal response during R.E.M. Took 2 extra strength Tylenol , 2 sudafed and ice. The 3 most commonly used medications for injection therapy are Trimix, Bimix, and papaverine. More than four-hour erections are risky and are regarded as a medical emergency. Happy first anniversary which I trust you and Ted will celebrate well. I agree tried on a whim and was AMAZED at what it did for rigidness and. 2 and 1/2 units would be VERY small dose. If you want to learn more about this subject, I suggest you join the prostate pointers mailing list PC and Intimacy. Precision Rx Telemed is about personal wellness. Designed and Created by. Patients should always use the smallest effective dose, as, after a certain point, there is no benefit to increasing the dosage further, and the risk of side effects will increase significantly. The PGE-1 amount is really the most important. No side effects at all Mine easily lasts 6 months in the fridge and long as I am care to keep it refrigerated. Constant erections can be a concern with this medication, as they can with all ED treatments. But in the real world, it can take some time, and many have reported erections that neared priapism. I thought I would have to embarass myself and check into an ER!! Not deterred, and having to wait almost a month to heal (believe me guys its no fun). tried trimix 30 then 50 units. I assume you know that Trimix is a mix of papaverine (vasodilator), phentolamine (alpha-blocker), and prostaglandin E1 (PGE1), a variant of alprostadil. When done correctly there should be NO pain. It also happens to be my birthday. If he has erections in his sleep without any trimix at all, that is FANTASTIC news. Any other cases of this still reluctant to try needle. that took about 2 weeks and I use every two days. And then- Trimix. Some guys are hypersensitive to Trimix. Brand names: Edex, Caverject, Muse, Caverject Impulse, Prostin VR Pediatric, Edex Refill Alprostadil has an average rating of 7.1 out of 10 from a total of 156 reviews for the treatment of Erectile Dysfunction. Next night used 10 cc it was ok. Coming to the cost, based on the dosage, the prices can range anywhere from $400 to even $2000. Prostaglandine E1 (50mcg) papaverine (30mg) phentolamine (1.5mg) This is my trimix dosage. cc or cubic centimeter a measure of volume, equivalent to 1 milliliter (mL) of liquid. The active ingredients in the penile injections Trimix and Quadmix are alprostadil, papaverine, phentolamine and atropine. Hi Leah , if their response is close to a 3 they remain in the clinic for further monitoring. Trimix is a prescription medication, and naturally has risks associated with it. An open discussion on Erectile Dysfunction. Then I collapsed. The content weve included in this guide is merely meant to be informational and does not constitute medical advice. We are doing it right. I experienced this problem and Lidocaine was the solution. I use less than 0.1cc at a time and it works well. After they checked for blood flow they gave me a test injection. 4. Once past the initial apprehension of sticking a needle in Mr. New video added to the list. If not roughly whats your copay? Any suggestions on having an orgasm while using Trimix? You are using an out of date browser. It is only used as a secondary treatment for ED because it is typically more potent and effective (and hence slightly riskier). Allow 15 minutes for medicine to work. Tried all the oral medications with no success. Trimix Injection Site Below are step-by-step instructions detailing how to properly use your penile injection at home without a doctor. Do You REALLY need to take TRIMIX? This misinformation can be dangerous to newbies. Its our desire at Precision Rx Telemed to altaer the narratives and Q2. Trimix has been proven to be quite helpful at treating ED, particularly in men who have not responded well to oral treatments. So I've tried Trimix 5 times with varied results. If so, a prescription will be issued and transferred to the associated compounding pharmacy to be filled and sent to your home for you to start using. Like most, I kind of sphinctered up at the thought of pressing a needle into my penis. It is only one injection per time, and you . For those of you haveing little luck with the trimix there is a Qudmix they just added atropine to the mix.. I lost 90% of my erection ability and have recovered about 60% since. Trimix is not good for your penis, and it does not increase the size. I went to the middle strength Trimix offering, from the formulary the clinic I attend uses. A prolonged erection, known as priapism, may occur. These ingredients work by relaxing the smooth muscle and opening the blood vessels in your penis, causing an erection. Since I had little reaction to 15 units, he suggested I go up by 10 units (25) for my trial run with wife. A little sore. Once reconstituted with 5 mL of Bacteriostatic Water: Papaverine HCl 30 mg/mL, Phentolamine Mesylate 2 mg/mL, Prostaglandin E1 20 mcg/mL, Atropine Sulfate 200 mcg/mL. My doctor injected me with some med that helped in calming down my erections. This can then be adjusted upward by small amounts based on patient feedback and experience, up to a certain upper limit, until satisfactory results are seen. I lowered my A1Cs to 5.6, but still had these problems. Save my name, email, and website in this browser for the next time I comment. That equates to 0.025 ml.. Ive just recently started using Trimix, the ur recommended 0.2 ml 0.5, I used 0.2, my erection was off the charts. Maximum dose: 3 times per week, with at least 24 hours between each use. Sadly I will never drill concrete with my stick, even a bowl of jello is a challenge. what happens if you do more? But I can tell you that trial and error is normal with Trimix. You must feel the needle penetrate twice. I have been using Tri-Mix for about 2 years now. The most frequent adverse effects are soreness at the injection site, minor bleeding that occurs right away after administration, and some initial discomfort. When taking the injections, remember the. 47 year old Type 1 diabetic. . Do you think you hit the right area / angle when you tried the lower dosages? I noticed it was coming up on an hour. though my condition is different from what i have read here, i share a side effect. it took 3 seconds why i thought this was a problem i don't know.